HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: WDR12 (Q9GZL7)
Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12)
Gene: WDR12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21145461
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 423
+	Hs
		964929 CUL4B_HUMAN (1-913): 0: 1185: 100.00		WDR5_HUMAN (228-421): 3.17e-49: 171: 25.89
+	Hs
		1115283 CUL4B_HUMAN (1-913): 0: 1185: 100.00		WDR5B_HUMAN (232-421): 3.25e-45: 161: 29.02
+	Hs
		1115313 CUL4B_HUMAN (1-913): 0: 1185: 100.00		POC1B_HUMAN (251-420): 1.11e-43: 160: 25.43
+	Hs
		1115343 CUL4B_HUMAN (1-913): 0: 1185: 100.00		FBXW7_HUMAN (220-421): 1.31e-37: 146: 19.67
+	Hs
		1085651 CUL4B_HUMAN (1-913): 0: 1185: 100.00		TBL3_HUMAN (151-420): 4.32e-28: 119: 14.39
+	Hs
		845298 CUL4B_HUMAN (1-913): 0: 1185: 100.00		LIS1_HUMAN (294-421): 3.33e-29: 119: 23.08
+	Hs
		1115353 CUL4B_HUMAN (1-913): 0: 1185: 100.00		SNR40_HUMAN (327-421): 1.27e-16: 82.5: 19.79
+	Hs
		1115406 CUL4B_HUMAN (1-913): 0: 1185: 100.00		TBL1R_HUMAN (10-128): 6.66e-13: 72.1: 13.01
+	Hs
		261407 CUL4B_HUMAN (1-913): 0: 1185: 100.00		TBL1X_HUMAN (9-128): 7e-13: 72.1: 12.90
+	Hs
		1115483 CUL4B_HUMAN (1-913): 0: 1185: 100.00		FBW1B_HUMAN (111-409): 4.12e-10: 63.5: 24.76
+	Hs
		964928 CUL4A_HUMAN (161-913): 0: 957: 81.83		WDR5_HUMAN (228-421): 3.17e-49: 171: 25.89
+	Hs
		1114921 CUL4A_HUMAN (161-913): 0: 957: 81.83		WDR5B_HUMAN (232-421): 3.25e-45: 161: 29.02
+	Hs
		1114950 CUL4A_HUMAN (161-913): 0: 957: 81.83		POC1B_HUMAN (251-420): 1.11e-43: 160: 25.43
+	Hs
		845297 CUL4A_HUMAN (161-913): 0: 957: 81.83		LIS1_HUMAN (294-421): 3.33e-29: 119: 23.08
+	Hs
		1115158 CUL4A_HUMAN (161-913): 0: 957: 81.83		FBW1A_HUMAN (295-418): 7.19e-22: 100: 25.81
+	Hs
		1114994 CUL4A_HUMAN (161-913): 0: 957: 81.83		SNR40_HUMAN (327-421): 1.27e-16: 82.5: 19.79
+	Hs
		964927 CUL3_HUMAN (186-913): 0: 854: 37.19		WDR5_HUMAN (228-421): 3.17e-49: 171: 25.89
+	Hs
		1115136 CUL4A_HUMAN (161-913): 0: 957: 81.83		FBW1B_HUMAN (111-409): 4.12e-10: 63.5: 24.76
+	Hs
		209262 CUL3_HUMAN (186-913): 0: 854: 37.19		PRP4_HUMAN (187-419): 1.22e-44: 164: 15.57
+	Hs
		1113779 CUL3_HUMAN (186-913): 0: 854: 37.19		POC1B_HUMAN (251-420): 1.11e-43: 160: 25.43