HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 305
+	Hs
		845298 CUL4B_HUMAN (1-913): 0: 1185: 100.00		LIS1_HUMAN (2-262): 1.72e-86: 266: 20.64
+	Hs
		1115343 CUL4B_HUMAN (1-913): 0: 1185: 100.00		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		1115353 CUL4B_HUMAN (1-913): 0: 1185: 100.00		SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42
+	Hs
		964929 CUL4B_HUMAN (1-913): 0: 1185: 100.00		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		1115283 CUL4B_HUMAN (1-913): 0: 1185: 100.00		WDR5B_HUMAN (179-304): 8.24e-38: 138: 30.95
+	Hs
		1115313 CUL4B_HUMAN (1-913): 0: 1185: 100.00		POC1B_HUMAN (2-121): 1.9e-19: 90: 15.86
+	Hs
		1115047 CUL4A_HUMAN (161-913): 0: 957: 81.83		SKI8_HUMAN (1-305): 9.09e-102: 301: 100.00
+	Hs
		1085651 CUL4B_HUMAN (1-913): 0: 1185: 100.00		TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93
+	Hs
		845297 CUL4A_HUMAN (161-913): 0: 957: 81.83		LIS1_HUMAN (2-262): 1.72e-86: 266: 20.64
+	Hs
		1114244 CUL3_HUMAN (186-913): 0: 854: 37.19		SKI8_HUMAN (1-305): 9.09e-102: 301: 100.00
+	Hs
		1114994 CUL4A_HUMAN (161-913): 0: 957: 81.83		SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42
+	Hs
		1114438 CUL3_HUMAN (186-913): 0: 854: 37.19		NLE1_HUMAN (7-304): 8.2e-91: 279: 21.61
+	Hs
		964928 CUL4A_HUMAN (161-913): 0: 957: 81.83		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		1114921 CUL4A_HUMAN (161-913): 0: 957: 81.83		WDR5B_HUMAN (179-304): 8.24e-38: 138: 30.95
+	Hs
		1114950 CUL4A_HUMAN (161-913): 0: 957: 81.83		POC1B_HUMAN (2-121): 1.9e-19: 90: 15.86
+	Hs
		1115073 CUL4A_HUMAN (161-913): 0: 957: 81.83		GBB4_HUMAN (59-302): 1.04e-12: 69.3: 22.00
+	Hs
		964927 CUL3_HUMAN (186-913): 0: 854: 37.19		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	At
		99584 CUL4_ARATH (147-913): 0: 920: 55.73		KTN82_ARATH (118-302): 1.41e-14: 76.3: 24.32
+	Hs
		1113779 CUL3_HUMAN (186-913): 0: 854: 37.19		POC1B_HUMAN (2-121): 1.9e-19: 90: 15.86
+	Hs
		209262 CUL3_HUMAN (186-913): 0: 854: 37.19		PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68