Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: RPGF2 (Q8CHG7)
Rap guanine nucleotide exchange factor 2 (Cyclic nucleotide ras GEF) (CNrasGEF) (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF-1) (Ras/Rap1-associating GEF-1)
Gene: Rapgef2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27507650, 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ_6, PDZ~SAM_1, PDZ~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0043005 - neuron projection
GO:0048167 - regulation of synaptic plasticity
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 1496
+ Hs
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Last updated: 15 Jul 2024