HitPredict

Interactor 1: SEK1 (G5EDF7)
Dual specificity mitogen-activated protein kinase kinase sek-1 (MAP kinase kinase sek-1) (EC 2.7.12.2)
Gene: sek-1

Interactor 2: PMK1 (Q17446)
Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (Stress-activated protein kinase pmk-1) (p38 MAP kinase 1)
Gene: pmk-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 20369020
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0000302 - response to reactive oxygen species
GO:0000303 - response to superoxide
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 336
Ce

1 377
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Service provided by Combinatics, Japan

Last updated: 11Aug2025