HitPredict

Interactor 1: NSE1 (Q53EK2)
Non-structural maintenance of chromosomes element 1 (Non-SMC element 1) (EC 2.3.2.27)
Gene: NSE1

Interactor 2: NSE3 (Q9Y7U4)
Non-structural maintenance of chromosome element 3 (Non-SMC element 3)
Gene: NSE3

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

Property	Details
Experiments	15601840, 15331764, 32546830, 21364888
Identification Methods	pull down, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	MAGE~SMC_Nse1
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0006281 - DNA repair GO:0030915 - Smc5-Smc6 complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 232 Sp			1 328
+	Hs
		1261002 NSE1_HUMAN (5-223): 7.52e-96: 282: 28.76		NSE3_HUMAN (53-326): 1.39e-93: 282: 18.51
+	Mm
		1321620 NSE1_MOUSE (5-223): 1.53e-95: 281: 28.76		NSE3_MOUSE (33-328): 4.86e-94: 282: 19.00
+	Hs
		1261000 NSE1_HUMAN (5-223): 7.52e-96: 282: 28.76		MAGBA_HUMAN (39-318): 8.27e-90: 274: 16.22
+	Hs
		795650 NSE1_HUMAN (5-223): 7.52e-96: 282: 28.76		MAGA1_HUMAN (17-310): 3.52e-80: 248: 13.09
+	Hs
		1261005 NSE1_HUMAN (5-223): 7.52e-96: 282: 28.76		MAGF1_HUMAN (24-318): 2.93e-64: 207: 15.05
+	Hs
		1261006 NSE1_HUMAN (5-223): 7.52e-96: 282: 28.76		MAGE1_HUMAN (53-323): 3e-49: 178: 15.75