HitPredict

Interactor 1: G5EDV6 (G5EDV6)
IST1 homolog (Charged multivesicular body protein 8)
Gene: istr-1

Interactor 2: O16458 (O16458)
Charged multivesicular body protein 5
Gene: vps-60

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	29129923
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ist1~Snf7
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 432 Ce			1 217
+	Ce
		112134 G5EDV6_CAEEL (1-432): 6.37e-143: 416: 100.00		Q18886_CAEEL (2-210): 3.58e-38: 133: 20.57
+	Ce
		112135 G5EDV6_CAEEL (1-432): 6.37e-143: 416: 100.00		Q9BL60_CAEEL (1-207): 9.47e-27: 103: 15.87
+	Dm
		1485262 Q9VRY6_DROME (4-432): 3.33e-117: 350: 38.27		CHMP5_DROME (1-216): 1.95e-41: 142: 53.85
+	Dm
		122106 M9PHL4_DROME (4-432): 2.15e-107: 324: 38.05		CHMP5_DROME (1-216): 1.95e-41: 142: 53.85
+	Hs
		925688 IST1_HUMAN (3-431): 2.48e-106: 320: 35.90		CHMP5_HUMAN (1-217): 2.13e-43: 146: 59.82
+	Dm
		1345402 Q9VRY6_DROME (4-432): 3.33e-117: 350: 38.27		CHM4_DROME (2-198): 2.04e-30: 113: 26.26
+	Dm
		1484930 Q9VRY6_DROME (4-432): 3.33e-117: 350: 38.27		Q9VRJ5_DROME (2-211): 6.52e-30: 111: 15.71
+	Dm
		1469212 Q9VRY6_DROME (4-432): 3.33e-117: 350: 38.27		Q9VBI3_DROME (1-206): 1.8e-28: 109: 19.90
+	Dm
		122092 M9PHL4_DROME (4-432): 2.15e-107: 324: 38.05		CHM4_DROME (2-198): 2.04e-30: 113: 26.26
+	Hs
		925681 IST1_HUMAN (3-431): 2.48e-106: 320: 35.90		CHM4B_HUMAN (14-216): 1.12e-31: 116: 24.51
+	Dm
		122105 M9PHL4_DROME (4-432): 2.15e-107: 324: 38.05		Q9VRJ5_DROME (2-211): 6.52e-30: 111: 15.71
+	Dm
		122098 M9PHL4_DROME (4-432): 2.15e-107: 324: 38.05		Q9VBI3_DROME (1-206): 1.8e-28: 109: 19.90
+	Sc
		815040 IST1_YEAST (1-214): 1.32e-61: 203: 29.28		SNF7_YEAST (14-196): 2.14e-33: 121: 22.68
+	Sc
		923807 IST1_YEAST (1-214): 1.32e-61: 203: 29.28		VPS60_YEAST (1-208): 7.39e-29: 109: 27.65
+	Sc
		923808 IST1_YEAST (1-214): 1.32e-61: 203: 29.28		VPS20_YEAST (7-211): 5.25e-28: 107: 22.82