HitPredict

Interactor 1: ARHG7 (Q14155)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)
Gene: ARHGEF7

Interactor 2: ARHG7 (Q14155)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)
Gene: ARHGEF7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.680

The method score is based on:

Property Details
Experiments 15212761
Identification Methods pull down, two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, PH~PH, PH~RhoGEF, RhoGEF~RhoGEF, RhoGEF~SH3_2, SH3_2~SH3_2
Common GO terms GO:0001726 - ruffle
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
and 23 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 803
Hs

1 803
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Service provided by Combinatics, Japan

Last updated: 11Aug2025