HitPredict

Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Interactor 2: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 31980649, 31839598
Identification Methods affinity chromatography technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~PH, C1_1~RhoGEF, C1_1~SH2, CAMSAP_CH~PH, PH~PH, PH~RhoGEF, PH~SH3_1, RhoGEF~RhoGEF, RhoGEF~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0001784 - phosphotyrosine residue binding
GO:0002768 - immune response-regulating cell surface receptor signaling pathway
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 24 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 845
Hs

1 845
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025