HitPredict

Interactor 1: PP6R3 (Q5H9R7)
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)
Gene: PPP6R3

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 873 Hs			1 347
+	Hs
		1038440 PP6R3_HUMAN (1-873): 0: 854: 100.00		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		1126020 PP6R3_HUMAN (1-873): 0: 854: 100.00		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		1038825 PP6R1_HUMAN (1-872): 0: 670: 44.00		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		1288054 PP6R1_HUMAN (1-872): 0: 670: 44.00		HDA11_HUMAN (1-347): 1.17e-140: 403: 100.00
+	Hs
		203227 SYNJ1_HUMAN (459-873): 3.44e-31: 134: 13.04		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Mm
		1157748 SYNJ1_MOUSE (459-835): 9.86e-29: 126: 9.93		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Hs
		1038856 CABIN_HUMAN (613-873): 2.13e-24: 112: 14.56		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		1270548 CABIN_HUMAN (613-873): 2.13e-24: 112: 14.56		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		1038770 RERE_HUMAN (579-872): 2.17e-11: 70.3: 9.97		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Mm
		88461 D3Z656_MOUSE (560-868): 2.99e-09: 63: 11.00		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Hs
		1270490 RERE_HUMAN (579-872): 2.17e-11: 70.3: 9.97		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89