HitPredict

Interactor 1: M9NDL7 (M9NDL7)
RALBP1 associated Eps domain containing, isoform B
Gene: Reps

Interactor 2: Q9VDC3 (Q9VDC3)
AP complex subunit sigma
Gene: AP-2sigma

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 878 Dm			1 142
+	Dm
		112641 M9NDL7_DROME (1-878): 7.64e-79: 275: 100.00		O62530_DROME (1-138): 2.32e-42: 146: 16.67
+	Hs
		787877 EPS15_HUMAN (1-841): 2.5e-64: 234: 12.01		AP2S1_HUMAN (1-142): 4.85e-46: 148: 95.78
+	Hs
		787959 EPS15_HUMAN (1-841): 2.5e-64: 234: 12.01		AP2M1_HUMAN (1-138): 1.51e-41: 144: 15.22
+	Hs
		1244783 REPS2_HUMAN (3-589): 5.7e-45: 174: 23.62		AP2M1_HUMAN (1-138): 1.51e-41: 144: 15.22
+	Hs
		864098 REPS1_HUMAN (3-710): 1.11e-40: 163: 23.22		AP2S1_HUMAN (1-142): 4.85e-46: 148: 95.78
+	Hs
		1287459 REPS1_HUMAN (3-710): 1.11e-40: 163: 23.22		AP2M1_HUMAN (1-138): 1.51e-41: 144: 15.22
+	Ce
		725368 Q9U2T9_CAEEL (258-465): 2.85e-31: 134: 20.95		AP2M_CAEEL (1-138): 1.9e-43: 149: 15.94
+	Hs
		1349325 EHD2_HUMAN (245-351): 2.89e-20: 97.6: 29.91		AP1M2_HUMAN (2-142): 2.73e-44: 151: 20.14
+	Hs
		864076 ITSN1_HUMAN (2-96): 6.42e-20: 98.1: 16.84		AP2S1_HUMAN (1-142): 4.85e-46: 148: 95.78
+	Hs
		1078888 ITSN1_HUMAN (2-96): 6.42e-20: 98.1: 16.84		AP2M1_HUMAN (1-138): 1.51e-41: 144: 15.22
+	Hs
		1287516 EHD2_HUMAN (245-351): 2.89e-20: 97.6: 29.91		AP2M1_HUMAN (1-138): 1.51e-41: 144: 15.22
+	Hs
		864110 ITSN2_HUMAN (2-82): 4.57e-17: 88.9: 14.82		AP2S1_HUMAN (1-142): 4.85e-46: 148: 95.78
+	Hs
		1287515 ITSN2_HUMAN (2-82): 4.57e-17: 88.9: 14.82		AP2M1_HUMAN (1-138): 1.51e-41: 144: 15.22
+	At
		1196569 Q9LM78_ARATH (265-672): 1.69e-11: 70.3: 21.39		AP2S_ARATH (1-142): 1.23e-44: 144: 59.86
+	Hs
		864112 EP15R_HUMAN (3-744): 3.4e-09: 62.7: 10.43		AP2S1_HUMAN (1-142): 4.85e-46: 148: 95.78
+	Hs
		1287519 EP15R_HUMAN (3-744): 3.4e-09: 62.7: 10.43		AP2M1_HUMAN (1-138): 1.51e-41: 144: 15.22