HitPredict

Interactor 1: K2C72 (Q14CN4)
Keratin, type II cytoskeletal 72 (Cytokeratin-72) (CK-72) (Keratin-72) (K72) (Type II inner root sheath-specific keratin-K6irs2) (Type-II keratin Kb35)
Gene: KRT72

Interactor 2: KRT84 (Q9NSB2)
Keratin, type II cuticular Hb4 (Keratin-84) (K84) (Type II hair keratin Hb4) (Type-II keratin Kb24)
Gene: KRT84

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0030280 - structural constituent of skin epidermis GO:0031424 - keratinization GO:0045095 - keratin filament GO:0045109 - intermediate filament organization and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 511 Hs			1 600
+	Hs
		407364 K2C1_HUMAN (91-453): 3.34e-160: 471: 67.22		K2C7_HUMAN (92-487): 1.26e-146: 433: 62.56
+	Hs
		475769 K2C1B_HUMAN (44-453): 4.11e-161: 471: 56.92		K2C7_HUMAN (92-487): 1.26e-146: 433: 62.56
+	Hs
		1280864 K2C1B_HUMAN (44-453): 4.11e-161: 471: 56.92		KRT84_HUMAN (1-600): 6.01e-132: 400: 100.00
+	Hs
		551596 K2C3_HUMAN (97-443): 8.2e-157: 462: 71.63		KRT84_HUMAN (1-600): 6.01e-132: 400: 100.00
+	Hs
		407358 K2C1_HUMAN (91-453): 3.34e-160: 471: 67.22		K2C8_HUMAN (83-508): 1.98e-110: 341: 55.63
+	Hs
		437246 K2C1B_HUMAN (44-453): 4.11e-161: 471: 56.92		K2C8_HUMAN (83-508): 1.98e-110: 341: 55.63
+	Hs
		437069 K2C3_HUMAN (97-443): 8.2e-157: 462: 71.63		K2C8_HUMAN (83-508): 1.98e-110: 341: 55.63
+	Hs
		227198 K2C8_HUMAN (33-472): 1.04e-158: 461: 55.91		KRT86_HUMAN (56-536): 1.51e-89: 287: 59.46
+	Hs
		341722 K2C1_HUMAN (91-453): 3.34e-160: 471: 67.22		K2C75_HUMAN (1-479): 7.03e-82: 269: 50.82
+	Hs
		341801 K2C1B_HUMAN (44-453): 4.11e-161: 471: 56.92		K2C75_HUMAN (1-479): 7.03e-82: 269: 50.82
+	Hs
		341729 K2C3_HUMAN (97-443): 8.2e-157: 462: 71.63		K2C75_HUMAN (1-479): 7.03e-82: 269: 50.82
+	Hs
		407377 K2C1_HUMAN (91-453): 3.34e-160: 471: 67.22		K2C5_HUMAN (1-479): 3.8e-75: 252: 51.32
+	Hs
		566414 K2C1B_HUMAN (44-453): 4.11e-161: 471: 56.92		K2C5_HUMAN (1-479): 3.8e-75: 252: 51.32
+	Hs
		551532 K2C3_HUMAN (97-443): 8.2e-157: 462: 71.63		K2C5_HUMAN (1-479): 3.8e-75: 252: 51.32
+	Hs
		385298 K2C1B_HUMAN (44-453): 4.11e-161: 471: 56.92		K2C6A_HUMAN (1-479): 1.04e-70: 239: 52.98
+	Hs
		385226 K2C3_HUMAN (97-443): 8.2e-157: 462: 71.63		K2C6A_HUMAN (1-479): 1.04e-70: 239: 52.98
+	Hs
		300543 K2C1_HUMAN (91-453): 3.34e-160: 471: 67.22		KRT36_HUMAN (65-476): 3.73e-61: 211: 27.12
+	Hs
		300586 K2C1B_HUMAN (44-453): 4.11e-161: 471: 56.92		KRT36_HUMAN (65-476): 3.73e-61: 211: 27.12
+	Hs
		551555 K2C3_HUMAN (97-443): 8.2e-157: 462: 71.63		K1H2_HUMAN (54-476): 5.19e-62: 213: 22.64
+	Hs
		300547 K2C3_HUMAN (97-443): 8.2e-157: 462: 71.63		KRT36_HUMAN (65-476): 3.73e-61: 211: 27.12