HitPredict

Interactor 1: MRCKA (Q5VT25)
Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPA

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1732 Hs			1 783
+	Hs
		1172454 MRCKB_HUMAN (1-1731): 0: 1417: 60.38		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		148970 CTRO_HUMAN (4-1044): 3.09e-128: 447: 24.43		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		682189 AKT2_HUMAN (13-391): 2.91e-129: 414: 30.65		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		681909 AKT1_HUMAN (13-404): 1.23e-128: 413: 31.51		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172202 TNIK_HUMAN (53-905): 4.35e-97: 346: 15.60		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1069619 STK38_HUMAN (66-404): 1.24e-89: 302: 45.07		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172335 ST38L_HUMAN (66-416): 1.26e-88: 299: 43.15		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		254493 ROCK2_HUMAN (373-1052): 1.4e-22: 108: 12.07		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Mm
		949339 TNIK_MOUSE (53-700): 2.14e-94: 337: 15.88		TRI46_MOUSE (1-769): 7.66e-98: 322: 20.36
+	Hs
		1318737 TNIK_HUMAN (53-905): 4.35e-97: 346: 15.60		TRIM2_HUMAN (194-767): 1.51e-82: 280: 15.95
+	Mm
		949424 TNIK_MOUSE (53-700): 2.14e-94: 337: 15.88		TRIM3_MOUSE (190-767): 6.68e-78: 268: 14.85
+	Hs
		149045 CTRO_HUMAN (4-1044): 3.09e-128: 447: 24.43		CMYA5_HUMAN (262-606): 5.31e-36: 149: 19.32
+	Hs
		1069648 STK38_HUMAN (66-404): 1.24e-89: 302: 45.07		TRIM6_HUMAN (195-774): 1.16e-86: 284: 12.69
+	Hs
		1049033 STK38_HUMAN (66-404): 1.24e-89: 302: 45.07		TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80
+	Hs
		149258 CTRO_HUMAN (4-1044): 3.09e-128: 447: 24.43		TRIM4_HUMAN (1-123): 1.51e-09: 63.2: 18.70
+	Hs
		537127 TNIK_HUMAN (53-905): 4.35e-97: 346: 15.60		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		537140 ST38L_HUMAN (66-416): 1.26e-88: 299: 43.15		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Mm
		1143596 ST38L_MOUSE (66-416): 9.21e-88: 296: 42.89		TRI27_MOUSE (105-456): 7.29e-11: 67.4: 14.77
+	Hs
		1052661 STK38_HUMAN (66-404): 1.24e-89: 302: 45.07		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		537089 LATS2_HUMAN (65-376): 3.53e-75: 275: 41.23		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77