Interactor 1: SYK (Q15046)
Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)
Gene: KARS1
Interactor 2: SYDM (Q6PI48)
Aspartate--tRNA ligase, mitochondrial (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)
Gene: DARS2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9878398 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | tRNA-synt_2~tRNA-synt_2, tRNA-synt_2~tRNA_anti-codon, tRNA_anti-codon~tRNA_anti-codon |
| Common GO terms | GO:0000049 - tRNA binding GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix and 1 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
