Interactor 1: SYNC (O43776)
Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) (Asparaginyl-tRNA synthetase 1)
Gene: NARS1

Interactor 2: SYNC (O43776)
Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) (Asparaginyl-tRNA synthetase 1)
Gene: NARS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AsnRS_N~AsnRS_N, tRNA-synt_2~tRNA-synt_2, tRNA-synt_2~tRNA_anti-codon, tRNA_anti-codon~tRNA_anti-codon
Common GO terms GO:0003676 - nucleic acid binding
GO:0004816 - asparagine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 548
Hs

1 548
+ Sc
+ Sc
+ Hs
+ Mm
+ Hs
+ Sc
+ Zm
+ Ec
+ Ec
+ Ec
+ Sc
+ Ec
+ Hs
+ Ec

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Last updated: 11Aug2025