Interactor 1: MCM7 (Q61881)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog)
Gene: MCM7

Interactor 2: SLD5 (Q99LZ3)
DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]
Gene: Gins4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 33590678, 35920641
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~Sld5, MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0006268 - DNA unwinding involved in DNA replication
GO:0071162 - CMG complex
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 719
Mm

1 223
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Dm
+ Sc
+ Sc
+ Dm
+ Sc
+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024