HitPredict

Interactor 1: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Interactor 2: UBE2N (Q9EQX9)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 810 Rn			1 152
+	Rn
		88580 UBC_RAT (1-810): 0: 1000: 100.00		UB2D1_RAT (4-149): 3.69e-80: 235: 45.89
+	Xl
		919927 Q7SY79_XENLA (229-801): 0: 702: 96.68		UB2D2_XENLA (4-149): 1.3e-79: 233: 45.89
+	Hs
		476604 UBC_HUMAN (1-533): 0: 662: 99.81		UB2D4_HUMAN (4-149): 5.01e-81: 237: 45.89
+	Hs
		475501 UBC_HUMAN (1-533): 0: 662: 99.81		UB2D1_HUMAN (4-149): 3.69e-80: 235: 45.89
+	Hs
		475586 UBC_HUMAN (1-533): 0: 662: 99.81		UB2D2_HUMAN (4-149): 1.3e-79: 233: 45.89
+	Hs
		475550 UBC_HUMAN (1-533): 0: 662: 99.81		UB2D3_HUMAN (4-149): 1.87e-78: 230: 45.21
+	Hs
		476218 UBC_HUMAN (1-533): 0: 662: 99.81		UB2E2_HUMAN (1-149): 1.4e-75: 225: 44.30
+	Hs
		476155 UBC_HUMAN (1-533): 0: 662: 99.81		UB2E3_HUMAN (1-149): 3.63e-75: 224: 44.30
+	Hs
		475504 UBC_HUMAN (1-533): 0: 662: 99.81		UB2E1_HUMAN (1-149): 1.96e-73: 219: 44.97
+	Hs
		475552 UBC_HUMAN (1-533): 0: 662: 99.81		UBE2N_HUMAN (1-152): 9.25e-74: 218: 99.34
+	Hs
		475485 UBC_HUMAN (1-533): 0: 662: 99.81		UBE2A_HUMAN (1-151): 1.32e-70: 211: 38.16
+	Hs
		475597 UBC_HUMAN (1-533): 0: 662: 99.81		UBE2B_HUMAN (1-151): 6.47e-70: 209: 38.82
+	Dm
		639414 Q9W418_DROME (305-801): 0: 604: 96.18		UBCD1_DROME (4-149): 1.68e-79: 233: 47.95
+	Dr
		94560 F1QHN6_DANRE (305-801): 0: 602: 96.18		Q7T3F3_DANRE (1-152): 3.84e-72: 214: 98.03
+	Hs
		476424 UBC_HUMAN (1-533): 0: 662: 99.81		UBE2T_HUMAN (7-148): 1.25e-38: 131: 45.89
+	Sc
		477103 UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73		UBC4_YEAST (1-149): 1.77e-79: 233: 45.64
+	Sc
		477372 UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73		UBC13_YEAST (1-150): 2.52e-70: 210: 69.33
+	At
		715116 UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22		UBC8_ARATH (4-149): 2.23e-80: 235: 45.89
+	At
		715132 UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22		UBC9_ARATH (4-149): 5.6e-80: 234: 45.89
+	At
		715147 UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22		UBC10_ARATH (4-149): 7.86e-80: 234: 45.21