HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSB3 (P49720)
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome subunit beta-3) (beta-3) (Proteasome theta chain)
Gene: PSMB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 205
+	Hs
		681124 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB3_HUMAN (1-205): 2.1e-71: 217: 100.00
+	Hs
		681109 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB6_HUMAN (7-200): 4.65e-70: 215: 22.68
+	Hs
		680813 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSB3_HUMAN (1-205): 2.1e-71: 217: 100.00
+	Hs
		680780 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSB6_HUMAN (7-200): 4.65e-70: 215: 22.68
+	Dm
		821814 PSA2_DROME (1-178): 4.05e-76: 229: 37.08		PSB1_DROME (2-205): 3.64e-70: 215: 26.51
+	Hs
		681105 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB8_HUMAN (8-205): 4.54e-67: 208: 22.73
+	Hs
		681110 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB5_HUMAN (8-197): 3.58e-66: 205: 22.63
+	Hs
		680776 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSB8_HUMAN (8-205): 4.54e-67: 208: 22.73
+	Hs
		633597 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB1_HUMAN (2-205): 2.39e-65: 203: 23.94
+	Hs
		680781 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSB5_HUMAN (8-197): 3.58e-66: 205: 22.63
+	Dm
		47749 PSA2_DROME (1-178): 4.05e-76: 229: 37.08		A0AQH0_DROME (7-199): 4.7e-66: 204: 24.35
+	Dm
		821841 PSA2_DROME (1-178): 4.05e-76: 229: 37.08		Q7K148_DROME (8-195): 2.73e-65: 204: 23.94
+	Hs
		633596 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSB1_HUMAN (2-205): 2.39e-65: 203: 23.94
+	Hs
		681100 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA2_HUMAN (8-205): 3.14e-64: 199: 14.85
+	Hs
		681107 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA5_HUMAN (8-203): 1.11e-63: 198: 12.20
+	Hs
		681106 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB9_HUMAN (6-200): 1.41e-63: 197: 23.08
+	Dm
		821862 PSA2_DROME (1-178): 4.05e-76: 229: 37.08		Q8T8V8_DROME (8-196): 1.16e-63: 201: 20.11
+	Hs
		680769 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSA2_HUMAN (8-205): 3.14e-64: 199: 14.85
+	Hs
		680778 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSA5_HUMAN (8-203): 1.11e-63: 198: 12.20
+	Hs
		680777 PSA1_HUMAN (1-177): 5.79e-76: 229: 29.21		PSB9_HUMAN (6-200): 1.41e-63: 197: 23.08