HitPredict

Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Interactor 2: RTL9 (Q8NET4)
Retrotransposon Gag-like protein 9 (Retrotransposon gag domain-containing protein 1) (Tumor antigen BJ-HCC-23)
Gene: RTL9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27634302
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 746 Hs			1 1388
+	Hs
		590286 EZH2_HUMAN (1-746): 0: 864: 100.00		MUC1_HUMAN (193-1182): 1.4e-51: 201: 13.06
+	Hs
		1155689 EZH2_HUMAN (1-746): 0: 864: 100.00		MUC4_HUMAN (32-1170): 2.23e-42: 173: 11.22
+	Hs
		1155795 EZH2_HUMAN (1-746): 0: 864: 100.00		CHD8_HUMAN (55-725): 3.13e-32: 139: 11.06
+	Hs
		1067381 EZH2_HUMAN (1-746): 0: 864: 100.00		EP300_HUMAN (319-1136): 3e-27: 123: 12.81
+	Hs
		1155848 EZH2_HUMAN (1-746): 0: 864: 100.00		RRBP1_HUMAN (99-552): 1.12e-15: 84.9: 9.91
+	Hs
		355522 NSD2_HUMAN (275-729): 1.3e-91: 314: 16.03		MDC1_HUMAN (2-521): 5.07e-13: 76.7: 10.04
+	Hs
		1419516 NSD3_HUMAN (275-729): 8.3e-70: 251: 14.42		CHD8_HUMAN (55-725): 3.13e-32: 139: 11.06
+	Hs
		1129701 NSD1_HUMAN (275-729): 2.84e-90: 312: 15.82		MDC1_HUMAN (2-521): 5.07e-13: 76.7: 10.04
+	Hs
		1129732 SETD2_HUMAN (190-732): 1.93e-89: 310: 16.64		MDC1_HUMAN (2-521): 5.07e-13: 76.7: 10.04
+	Hs
		1067609 EHMT2_HUMAN (467-732): 1.85e-68: 247: 24.21		EP300_HUMAN (319-1136): 3e-27: 123: 12.81
+	Hs
		175932 SET1A_HUMAN (611-732): 3.2e-18: 92: 38.71		CHD8_HUMAN (55-725): 3.13e-32: 139: 11.06
+	Hs
		1041572 KMT2A_HUMAN (606-733): 6.92e-19: 94.4: 39.54		CBP_HUMAN (245-1146): 1.1e-30: 134: 12.61
+	Hs
		175916 SET1A_HUMAN (611-732): 3.2e-18: 92: 38.71		CBP_HUMAN (245-1146): 1.1e-30: 134: 12.61
+	Hs
		175878 SET1A_HUMAN (611-732): 3.2e-18: 92: 38.71		EP300_HUMAN (319-1136): 3e-27: 123: 12.81
+	Hs
		1041523 KMT2A_HUMAN (606-733): 6.92e-19: 94.4: 39.54		NCOA6_HUMAN (4-1169): 3.36e-10: 67.4: 8.27
+	Hs
		1130610 SET1B_HUMAN (619-732): 1.39e-18: 93.2: 40.52		NCOA6_HUMAN (4-1169): 3.36e-10: 67.4: 8.27
+	Dm
		1208012 SET1_DROME (611-732): 1.28e-18: 93.2: 38.71		Q9VLS7_DROME (1-647): 6.19e-09: 63.2: 8.92