HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37166352
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0008270 - zinc ion binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 1210
+	Hs
		1067608 EP300_HUMAN (1-2414): 0: 1100: 100.00		ASPP1_HUMAN (755-937): 2.38e-15: 83.5: 16.67
+	Hs
		592931 EP300_HUMAN (1-2414): 0: 1100: 100.00		ANK1_HUMAN (254-636): 1.05e-13: 78.6: 8.08
+	Hs
		674295 BRD2_HUMAN (1035-1159): 9.61e-30: 131: 31.20		EHMT2_HUMAN (21-1210): 0: 903: 100.00
+	Hs
		1141266 BRD3_HUMAN (1055-1159): 9.1e-30: 130: 30.48		EHMT2_HUMAN (21-1210): 0: 903: 100.00
+	Hs
		674337 BRD2_HUMAN (1035-1159): 9.61e-30: 131: 31.20		EHMT1_HUMAN (1-1209): 0: 666: 45.16
+	Hs
		1141316 BRD3_HUMAN (1055-1159): 9.1e-30: 130: 30.48		EHMT1_HUMAN (1-1209): 0: 666: 45.16
+	Hs
		177339 TRI33_HUMAN (608-1201): 7.14e-42: 171: 14.59		ANR28_HUMAN (584-1085): 2.49e-84: 299: 17.82
+	Hs
		174458 TRI66_HUMAN (268-1197): 3.14e-41: 169: 12.47		ANR28_HUMAN (584-1085): 2.49e-84: 299: 17.82
+	Hs
		1129742 MDC1_HUMAN (455-1061): 1.21e-12: 76.3: 11.82		TNKS2_HUMAN (621-1046): 1.13e-74: 272: 20.59
+	Hs
		332404 MDC1_HUMAN (455-1061): 1.21e-12: 76.3: 11.82		TNKS1_HUMAN (621-1010): 4.78e-73: 268: 20.92
+	Hs
		1311352 PHIP_HUMAN (1068-1157): 6.81e-12: 73.6: 42.86		ANKH1_HUMAN (709-1047): 1.35e-35: 150: 16.86
+	Hs
		274205 PHIP_HUMAN (1068-1157): 6.81e-12: 73.6: 42.86		ANR17_HUMAN (708-1007): 4.56e-23: 109: 16.78