Interactor 1: UBE2S (Q16763)
Ubiquitin-conjugating enzyme E2 S (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme S) (E2-EPF) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-conjugating enzyme E2-EPF5) (Ubiquitin-protein ligase S)
Gene: UBE2S
Interactor 2: UBR4 (Q5T4S7)
E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (600 kDa retinoblastoma protein-associated factor) (p600) (N-recognin-4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600)
Gene: UBR4
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 37422473 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | E3_UbLigase_R4~UQ_con |
Common GO terms | GO:0004842 - ubiquitin-protein transferase activity GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 2 others more... |
Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 11Aug2025