HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: SYNE3 (Q6ZMZ3)
Nesprin-3 (KASH domain-containing protein 3) (KASH3) (Nuclear envelope spectrin repeat protein 3)
Gene: SYNE3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 975
+	Hs
		325935 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH2_HUMAN (279-930): 4.57e-20: 98.8: 10.04
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (299-923): 8.86e-20: 98: 10.57
+	Hs
		325612 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH8_HUMAN (351-936): 1.29e-19: 97.2: 10.08
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (286-930): 9.29e-19: 94.5: 9.72
+	Hs
		325605 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH3_HUMAN (351-938): 5.07e-18: 92.2: 9.11
+	Hs
		325936 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH13_HUMAN (351-928): 1.24e-17: 91: 9.73
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (343-935): 1.16e-17: 91: 9.05
+	Hs
		325724 LATS1_HUMAN (1-1130): 0: 934: 100.00		SPTN1_HUMAN (5-666): 4.38e-13: 76: 9.94
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (4-409): 6.25e-10: 65.6: 9.58
+	Hs
		1168705 LATS2_HUMAN (13-1121): 0: 751: 49.61		SYNE3_HUMAN (1-975): 1.69e-66: 243: 100.00
+	Hs
		809184 LATS2_HUMAN (13-1121): 0: 751: 49.61		UTRN_HUMAN (4-702): 5.63e-11: 69.2: 12.03
+	Hs
		725079 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04
+	Hs
		568568 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81
+	Hs
		681696 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04
+	Hs
		568567 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04
+	Hs
		610795 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH2_HUMAN (279-930): 4.57e-20: 98.8: 10.04
+	Hs
		528359 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH6_HUMAN (299-923): 8.86e-20: 98: 10.57
+	Rn
		1144340 AKT3_RAT (603-1081): 3.12e-141: 436: 24.34		SPTN2_RAT (5-282): 3.06e-11: 70: 13.31
+	Hs
		522538 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH1_HUMAN (286-930): 9.29e-19: 94.5: 9.72
+	Hs
		610802 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH4_HUMAN (343-935): 1.16e-17: 91: 9.05