HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: K1H1 (Q15323)
Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)
Gene: KRT31

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 416
+	Hs
		325699 LATS1_HUMAN (1-1130): 0: 934: 100.00		K1C17_HUMAN (49-367): 1.14e-116: 348: 59.88
+	Hs
		325601 LATS1_HUMAN (1-1130): 0: 934: 100.00		K1C16_HUMAN (54-382): 2.63e-115: 347: 58.36
+	Hs
		325794 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C73_HUMAN (3-412): 1.84e-99: 308: 22.33
+	Hs
		325658 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C6C_HUMAN (19-391): 4.07e-82: 264: 24.27
+	Hs
		325613 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C5_HUMAN (19-370): 5.48e-81: 261: 25.71
+	Hs
		325582 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C6A_HUMAN (19-391): 1.63e-80: 260: 24.27
+	Hs
		1071451 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		K1H1_HUMAN (1-416): 1.18e-87: 273: 100.00
+	Hs
		531325 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		K1C10_HUMAN (52-361): 3.18e-95: 298: 56.01
+	Hs
		1055200 AKT3_HUMAN (603-1081): 5.7e-143: 440: 24.54		K1H2_HUMAN (5-406): 5.07e-85: 268: 69.15
+	Hs
		681844 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		K1H2_HUMAN (5-406): 5.07e-85: 268: 69.15
+	Hs
		1071229 Q6PJG3_HUMAN (1-117): 2.14e-61: 207: 99.15		K1H1_HUMAN (1-416): 1.18e-87: 273: 100.00