HitPredict

Interactor 1: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Interactor 2: MICB (Q29980)
MHC class I polypeptide-related sequence B (MIC-B)
Gene: MICB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 855 Hs			1 383
+	Hs
		409403 DDR2_HUMAN (1-855): 0: 857: 100.00		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		409236 FGFR1_HUMAN (505-851): 3.16e-102: 337: 32.49		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		409262 FGFR2_HUMAN (522-851): 6.79e-102: 336: 34.42		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		409214 NTRK1_HUMAN (551-850): 4.93e-101: 333: 42.62		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		409396 NTRK3_HUMAN (551-849): 3.74e-99: 329: 42.63		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		409266 FGFR4_HUMAN (537-849): 5.05e-98: 325: 34.78		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		648533 FGFR4_HUMAN (537-849): 5.05e-98: 325: 34.78		MICB_HUMAN (1-383): 8.8e-140: 404: 100.00
+	Hs
		179591 MUSK_HUMAN (557-854): 3.26e-98: 327: 39.42		HLAB_HUMAN (1-316): 3.58e-133: 387: 27.47
+	Hs
		520859 NTRK3_HUMAN (551-849): 3.74e-99: 329: 42.63		HLAC_HUMAN (2-312): 4.87e-127: 371: 27.90
+	Hs
		179595 MUSK_HUMAN (557-854): 3.26e-98: 327: 39.42		HLAC_HUMAN (2-312): 4.87e-127: 371: 27.90
+	Hs
		719713 NTRK3_HUMAN (551-849): 3.74e-99: 329: 42.63		HLAF_HUMAN (3-340): 1.56e-121: 357: 26.93
+	Hs
		409224 IGF1R_HUMAN (535-845): 9.38e-58: 217: 40.13		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		409354 ROR1_HUMAN (556-849): 2.14e-58: 217: 39.87		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		1034162 ROR1_HUMAN (556-849): 2.14e-58: 217: 39.87		MICB_HUMAN (1-383): 8.8e-140: 404: 100.00
+	Hs
		409218 INSR_HUMAN (511-849): 1.55e-55: 210: 37.76		HLAA_HUMAN (2-340): 4.5e-141: 407: 27.51
+	Hs
		607362 ROR2_HUMAN (551-854): 8.5e-56: 209: 38.39		HLAG_HUMAN (1-316): 2.63e-133: 386: 26.85
+	Hs
		465377 IGF1R_HUMAN (535-845): 9.38e-58: 217: 40.13		HLAC_HUMAN (2-312): 4.87e-127: 371: 27.90
+	Hs
		520814 ROR2_HUMAN (551-854): 8.5e-56: 209: 38.39		HLAC_HUMAN (2-312): 4.87e-127: 371: 27.90
+	Hs
		568054 ROR2_HUMAN (551-854): 8.5e-56: 209: 38.39		HLAE_HUMAN (19-319): 7.01e-124: 363: 28.80
+	Rn
		67725 INSR_RAT (511-849): 4.36e-54: 206: 37.46		A7LNF8_RAT (24-309): 7.5e-117: 344: 29.59