HitPredict

Interactor 1: I3L3G9 (I3L3G9)
NudE neurodevelopment protein 1
Gene: NDE1

Interactor 2: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	24722188
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0008017 - microtubule binding GO:0051301 - cell division
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 642
+	Hs
		164083 NDEL1_HUMAN (3-265): 1.47e-59: 194: 61.65		NDC80_HUMAN (1-642): 3.95e-79: 265: 100.00
+	Hs
		164115 NDE1_HUMAN (1-265): 7.39e-59: 192: 100.00		NDC80_HUMAN (1-642): 3.95e-79: 265: 100.00
+	Hs
		164123 EP15R_HUMAN (6-243): 3.5e-45: 164: 17.72		NDC80_HUMAN (1-642): 3.95e-79: 265: 100.00
+	Hs
		773002 MYH9_HUMAN (2-221): 4.1e-29: 118: 18.18		UACA_HUMAN (191-641): 1.52e-30: 130: 13.88
+	Hs
		772658 EPS15_HUMAN (2-255): 9.18e-43: 157: 14.34		MYH9_HUMAN (197-640): 3.02e-13: 75.7: 10.94
+	Hs
		839759 EPS15_HUMAN (2-255): 9.18e-43: 157: 14.34		KT33B_HUMAN (266-567): 4.22e-09: 61.1: 19.17
+	Hs
		772645 MYH9_HUMAN (2-221): 4.1e-29: 118: 18.18		MYH10_HUMAN (175-642): 1.34e-16: 86.3: 11.04
+	Hs
		773112 MYH11_HUMAN (2-210): 5.89e-29: 118: 18.66		MYH10_HUMAN (175-642): 1.34e-16: 86.3: 11.04
+	Hs
		1217577 MRCKA_HUMAN (2-187): 2.34e-26: 110: 22.02		MRCKB_HUMAN (310-642): 8.31e-19: 93.3: 12.39
+	Rn
		236530 MRCKA_RAT (2-187): 8.04e-27: 111: 22.79		MRCKB_RAT (310-642): 6.47e-18: 90.6: 12.13
+	Hs
		556902 MYH9_HUMAN (2-221): 4.1e-29: 118: 18.18		MYH7_HUMAN (190-642): 2.72e-15: 82.1: 9.55
+	Rn
		236526 MRCKA_RAT (2-187): 8.04e-27: 111: 22.79		MRCKA_RAT (336-642): 2.36e-17: 88.7: 10.17
+	Mm
		98073 MYH9_MOUSE (2-213): 2.29e-28: 116: 17.45		DESP_MOUSE (190-642): 1.19e-15: 83.5: 15.27
+	Hs
		1217526 MRCKA_HUMAN (2-187): 2.34e-26: 110: 22.02		MRCKA_HUMAN (149-554): 5.83e-17: 87.5: 12.33
+	Hs
		772644 MYH9_HUMAN (2-221): 4.1e-29: 118: 18.18		MYH9_HUMAN (197-640): 3.02e-13: 75.7: 10.94
+	Hs
		772647 MYH11_HUMAN (2-210): 5.89e-29: 118: 18.66		MYH9_HUMAN (197-640): 3.02e-13: 75.7: 10.94
+	Hs
		773040 MYH9_HUMAN (2-221): 4.1e-29: 118: 18.18		MYO5C_HUMAN (194-519): 7.12e-13: 74.1: 9.71
+	Hs
		772935 MYH9_HUMAN (2-221): 4.1e-29: 118: 18.18		MY18A_HUMAN (189-559): 7.14e-12: 71.1: 12.47