HitPredict

Interactor 1: KIF2A (O00139)
Kinesin-like protein KIF2A (Kinesin-2) (hK2)
Gene: KIF2A

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	26496610, 26638075, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0005819 - spindle GO:0005829 - cytosol GO:0005874 - microtubule and 1 others more... GO:0120103 - centriolar subdistal appendage
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 706 Hs			1 1584
+	Hs
		1131824 KIF2C_HUMAN (1-702): 0: 641: 52.11		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		1131769 KIF2B_HUMAN (5-695): 0: 595: 54.62		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		116937 KIF2A_HUMAN (1-706): 0: 767: 100.00		C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28
+	Hs
		1131902 KIF3A_HUMAN (215-701): 5.7e-155: 466: 27.61		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		1233721 KIF2B_HUMAN (5-695): 0: 595: 54.62		C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28
+	Hs
		116814 KIF2A_HUMAN (1-706): 0: 767: 100.00		MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27
+	Hs
		116903 KIF2A_HUMAN (1-706): 0: 767: 100.00		TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21
+	Mm
		660029 KIF3A_MOUSE (215-699): 1.06e-150: 456: 27.17		ANK2_MOUSE (123-1379): 8.94e-11: 69.4: 13.83