HitPredict

Interactor 1: NBEL2 (Q6ZNJ1)
Neurobeachin-like protein 2
Gene: NBEAL2

Interactor 2: HUWE1 (Q7Z6Z7)
E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)
Gene: HUWE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29187380
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2754 Hs			1 4374
+	Hs
		1192155 FBXW7_HUMAN (2358-2525): 6.44e-20: 99.6: 13.64		HUWE1_HUMAN (1-4374): 0: 3240: 100.00
+	Hs
		929534 RACK1_HUMAN (2590-2751): 4.46e-20: 95.7: 14.02		HUWE1_HUMAN (1-4374): 0: 3240: 100.00
+	Mm
		1129463 WDR81_MOUSE (2494-2725): 1.16e-24: 116: 19.33		HUWE1_MOUSE (1-4374): 0: 3203: 96.37
+	Hs
		125310 WDR5_HUMAN (2586-2753): 1.82e-40: 156: 8.72		WWP2_HUMAN (3506-4372): 0: 624: 24.57
+	Hs
		125355 RACK1_HUMAN (2590-2751): 4.46e-20: 95.7: 14.02		WWP2_HUMAN (3506-4372): 0: 624: 24.57
+	Hs
		929669 RACK1_HUMAN (2590-2751): 4.46e-20: 95.7: 14.02		SMUF1_HUMAN (3772-4371): 0: 620: 32.84
+	Dm
		113977 GBLP_DROME (2540-2751): 1.96e-20: 96.9: 11.63		M9PB30_DROME (1419-2196): 1.16e-10: 70.7: 7.71