HitPredict

Interactor 1: CC141 (Q6ZP82)
Coiled-coil domain-containing protein 141 (Coiled-coil protein associated with myosin II and DISC1)
Gene: CCDC141

Interactor 2: DISC1 (Q9NRI5)
Disrupted in schizophrenia 1 protein
Gene: DISC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	12812986, 20956536
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1530 Hs			1 854
+	Mm
		93724 CC141_MOUSE (1-1530): 2.87e-104: 368: 72.72		DISC1_MOUSE (1-854): 0: 1251: 55.51
+	Hs
		164671 SPTN2_HUMAN (105-1195): 1.39e-42: 173: 12.01		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		963436 SPTB2_HUMAN (103-1235): 4e-38: 159: 12.52		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		522648 MYH7_HUMAN (453-1380): 1.61e-21: 104: 8.84		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		279893 TRIO_HUMAN (1254-1501): 6.29e-20: 99.4: 16.80		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		224728 KALRN_HUMAN (881-1510): 4.67e-16: 86.7: 14.31		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		1344836 MACF1_HUMAN (325-1179): 1.22e-15: 85.5: 10.75		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		725254 MYH10_HUMAN (1-524): 5.14e-13: 76.7: 10.12		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		974156 DYST_HUMAN (121-1133): 5.45e-11: 70.2: 13.52		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		1045542 SPTN1_HUMAN (539-1276): 8.81e-11: 69.2: 11.45		DISC1_HUMAN (18-854): 0: 1268: 100.00