HitPredict

Interactor 1: EMAL3 (Q32P44)
Echinoderm microtubule-associated protein-like 3 (EMAP-3)
Gene: EML3

Interactor 2: NEK1 (Q96PY6)
Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)
Gene: NEK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 1258
+	Hs
		1181486 EMAL3_HUMAN (1-896): 0: 574: 100.00		NEK9_HUMAN (4-261): 3.71e-61: 229: 42.31
+	Hs
		1181487 EMAL3_HUMAN (1-896): 0: 574: 100.00		NEK7_HUMAN (8-262): 1.89e-52: 188: 38.31
+	Hs
		1181502 EMAL3_HUMAN (1-896): 0: 574: 100.00		NEK6_HUMAN (8-267): 7.27e-52: 187: 36.84
+	Hs
		156755 WDR1_HUMAN (471-895): 1.21e-43: 169: 17.21		CTRO_HUMAN (2-1006): 2.28e-143: 481: 16.35
+	Hs
		157170 WDR5_HUMAN (60-390): 2.88e-38: 147: 11.40		CTRO_HUMAN (2-1006): 2.28e-143: 481: 16.35
+	Hs
		157993 WDR3_HUMAN (163-341): 1.63e-26: 118: 11.83		CTRO_HUMAN (2-1006): 2.28e-143: 481: 16.35
+	Dm
		1303738 NLE_DROME (147-584): 1.74e-55: 201: 11.34		AKT1_DROME (1-321): 4.8e-122: 392: 25.30
+	Hs
		157294 TBL3_HUMAN (101-298): 5.35e-18: 91.2: 9.26		CTRO_HUMAN (2-1006): 2.28e-143: 481: 16.35
+	Hs
		157418 TAF5_HUMAN (339-690): 6.4e-16: 84.5: 16.44		CTRO_HUMAN (2-1006): 2.28e-143: 481: 16.35
+	Hs
		270413 WDR1_HUMAN (471-895): 1.21e-43: 169: 17.21		AKT3_HUMAN (1-316): 1.98e-120: 384: 27.03
+	Hs
		157983 PRP19_HUMAN (361-664): 5.7e-12: 71.1: 15.71		CTRO_HUMAN (2-1006): 2.28e-143: 481: 16.35
+	Hs
		909242 PRP19_HUMAN (361-664): 5.7e-12: 71.1: 15.71		NEK4_HUMAN (1-266): 1.32e-78: 279: 50.56
+	Hs
		1350568 EMAL4_HUMAN (180-462): 2.07e-20: 99.3: 10.07		NEK9_HUMAN (4-261): 3.71e-61: 229: 42.31
+	Hs
		348916 EMAL2_HUMAN (581-896): 2.01e-25: 114: 13.94		NEK6_HUMAN (8-267): 7.27e-52: 187: 36.84
+	Hs
		134954 EMAL1_HUMAN (750-894): 8.87e-09: 61.5: 8.81		NEK9_HUMAN (4-261): 3.71e-61: 229: 42.31
+	Hs
		1351880 EMAL4_HUMAN (180-462): 2.07e-20: 99.3: 10.07		NEK7_HUMAN (8-262): 1.89e-52: 188: 38.31
+	Hs
		1438579 EMAL4_HUMAN (180-462): 2.07e-20: 99.3: 10.07		NEK6_HUMAN (8-267): 7.27e-52: 187: 36.84
+	Hs
		1334153 POC1A_HUMAN (824-894): 8.86e-09: 60.8: 22.54		NEK7_HUMAN (8-262): 1.89e-52: 188: 38.31
+	Sc
		598371 TUP1_YEAST (461-707): 3.03e-23: 108: 18.91		KIN3_YEAST (3-254): 1.18e-34: 140: 31.65