HitPredict

Interactor 1: PHAG1 (Q3U1F9)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)
Gene: Pag1

Interactor 2: NCK1 (Q99M51)
SH2/SH3 adapter protein Nck1 (Cytoplasmic protein Nck1) (NCK adapter protein 1) (Nck-1)
Gene: NCK1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	26512138
Identification Methods	affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	PAG~SH2
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 429 Mm			1 377
+	Mm
		237075 PHAG1_MOUSE (1-429): 0: 785: 100.00		NCK2_MOUSE (1-376): 1.08e-94: 289: 67.19
+	Mm
		813516 PHAG1_MOUSE (1-429): 0: 785: 100.00		FYN_MOUSE (5-130): 6.14e-22: 99.1: 21.09
+	Mm
		686963 PHAG1_MOUSE (1-429): 0: 785: 100.00		P85A_MOUSE (241-376): 7.01e-21: 96.4: 19.57
+	Mm
		1189725 PHAG1_MOUSE (1-429): 0: 785: 100.00		GRB2_MOUSE (3-62): 3.62e-17: 81.3: 28.33
+	Mm
		834252 PHAG1_MOUSE (1-429): 0: 785: 100.00		CSK_MOUSE (4-138): 2.43e-14: 75.9: 14.89
+	Mm
		1043254 PHAG1_MOUSE (1-429): 0: 785: 100.00		ITK_MOUSE (3-126): 1.94e-12: 70.6: 20.80
+	Rn
		740515 PHAG1_RAT (1-429): 0: 764: 89.51		CSK_RAT (4-138): 2.43e-14: 75.9: 14.89
+	Hs
		440751 PHAG1_HUMAN (1-429): 0: 705: 78.21		FYN_HUMAN (5-130): 6.38e-22: 99.1: 21.09
+	Hs
		841030 PHAG1_HUMAN (1-429): 0: 705: 78.21		FRK_HUMAN (3-127): 4.37e-20: 93.7: 22.39
+	Hs
		557496 PHAG1_HUMAN (1-429): 0: 705: 78.21		SRC_HUMAN (5-130): 2.54e-17: 85.5: 21.09
+	Hs
		987977 PHAG1_HUMAN (1-429): 0: 705: 78.21		GRB2_HUMAN (3-62): 3.51e-17: 81.3: 28.33
+	Hs
		834233 PHAG1_HUMAN (1-429): 0: 705: 78.21		CSK_HUMAN (4-138): 3.16e-14: 75.6: 14.89