HitPredict

Interactor 1: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Interactor 2: SKI8 (Q9ERF3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: Skic8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34161765
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MMS1_N~WD40, CPSF_A~WD40
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016055 - Wnt signaling pathway
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1140 Mm			1 305
+	Hs
		1157919 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SKI8_HUMAN (1-305): 8.88e-93: 279: 97.38
+	Hs
		964975 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5_HUMAN (3-217): 4.94e-65: 209: 20.81
+	Hs
		1157860 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SNR40_HUMAN (3-216): 1.35e-58: 193: 22.07
+	Hs
		845309 DDB1_HUMAN (1-1140): 0: 1445: 99.65		LIS1_HUMAN (2-178): 8.33e-50: 171: 14.21
+	Hs
		1157795 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5B_HUMAN (224-304): 9.39e-21: 92.3: 28.40
+	Hs
		1157737 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SMU1_HUMAN (33-187): 7.86e-10: 61.2: 22.84
+	Hs
		1085662 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL3_HUMAN (35-225): 6.46e-09: 58.9: 25.37
+	Hs
		1148041 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		SKI8_HUMAN (1-305): 8.88e-93: 279: 97.38
+	Hs
		1148066 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		NLE1_HUMAN (7-303): 6.55e-90: 277: 22.25
+	At
		1444134 DDB1A_ARATH (2-1140): 0: 1254: 52.18		VIP3_ARATH (6-135): 7.12e-24: 100: 24.27
+	At
		235879 DDB1B_ARATH (3-1140): 0: 1248: 51.00		VIP3_ARATH (6-135): 7.12e-24: 100: 24.27
+	At
		99585 DDB1A_ARATH (2-1140): 0: 1254: 52.18		KTN82_ARATH (118-283): 1.45e-14: 76.3: 25.90
+	At
		99583 DDB1B_ARATH (3-1140): 0: 1248: 51.00		KTN82_ARATH (118-283): 1.45e-14: 76.3: 25.90
+	Hs
		1147988 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		FBXW7_HUMAN (91-303): 9.77e-63: 212: 24.77
+	Hs
		284949 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		TAF5L_HUMAN (37-208): 3.6e-09: 59.3: 26.49
+	Hs
		1083446 CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01		NLE1_HUMAN (7-303): 6.55e-90: 277: 22.25
+	Hs
		209255 CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01		PRP4_HUMAN (106-304): 1.67e-57: 194: 22.71
+	Hs
		1083364 CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01		TAF5_HUMAN (35-302): 2.56e-18: 87: 22.22