HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29507117
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MMS1_N~WD40, CPSF_A~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 513
+	Hs
		1157932 DDB1_HUMAN (1-1140): 0: 1424: 100.00		WDR26_HUMAN (3-513): 2.74e-90: 291: 19.12
+	Mm
		1189812 DDB1_MOUSE (1-1140): 0: 1422: 99.65		WDR26_MOUSE (3-513): 9.21e-90: 289: 19.30
+	Hs
		845309 DDB1_HUMAN (1-1140): 0: 1424: 100.00		LIS1_HUMAN (4-472): 1.83e-91: 286: 15.13
+	Hs
		964975 DDB1_HUMAN (1-1140): 0: 1424: 100.00		WDR5_HUMAN (78-425): 4.43e-77: 247: 20.96
+	Hs
		261411 DDB1_HUMAN (1-1140): 0: 1424: 100.00		TBL1X_HUMAN (252-512): 1.5e-62: 215: 18.25
+	Hs
		1157912 DDB1_HUMAN (1-1140): 0: 1424: 100.00		TBL1R_HUMAN (252-512): 1.1e-62: 214: 16.96
+	Hs
		1157860 DDB1_HUMAN (1-1140): 0: 1424: 100.00		SNR40_HUMAN (51-333): 5.1e-39: 147: 14.34
+	Hs
		597363 DDB1_HUMAN (1-1140): 0: 1424: 100.00		GBB3_HUMAN (188-335): 4.96e-19: 90.4: 19.60
+	Hs
		1157795 DDB1_HUMAN (1-1140): 0: 1424: 100.00		WDR5B_HUMAN (427-512): 3.83e-18: 87.3: 22.09
+	Hs
		984129 DDB1_HUMAN (1-1140): 0: 1424: 100.00		GBB2_HUMAN (431-511): 1.7e-10: 64.5: 12.35
+	Hs
		1085662 DDB1_HUMAN (1-1140): 0: 1424: 100.00		TBL3_HUMAN (213-376): 4.86e-09: 60.8: 24.55
+	Hs
		1148066 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		NLE1_HUMAN (433-513): 4.7e-24: 106: 23.46
+	Hs
		284949 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		TAF5L_HUMAN (212-350): 1.64e-13: 75.1: 30.22
+	Hs
		1083446 CPSF1_HUMAN (4-527): 4.41e-117: 397: 15.87		NLE1_HUMAN (433-513): 4.7e-24: 106: 23.46