HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: PTPRJ (Q12913)
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)
Gene: PTPRJ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032760 - positive regulation of tumor necrosis factor production
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 1337
+	Hs
		121146 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		PTPRJ_HUMAN (1-1337): 0: 925: 100.00
+	Hs
		572351 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		PTPRJ_HUMAN (1-1337): 0: 925: 100.00
+	Hs
		814938 LEG7_HUMAN (224-354): 6.94e-39: 136: 37.04		PTPRJ_HUMAN (1-1337): 0: 925: 100.00
+	Hs
		119150 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		PTPRA_HUMAN (521-1304): 2.08e-110: 368: 19.78
+	Hs
		577026 LEG9B_HUMAN (1-355): 4.01e-139: 400: 94.94		PTPRA_HUMAN (521-1304): 2.08e-110: 368: 19.78
+	Hs
		119068 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		FINC_HUMAN (111-907): 2.55e-81: 297: 19.00
+	Hs
		121103 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		PTPRA_HUMAN (521-1304): 2.08e-110: 368: 19.78
+	Hs
		119173 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		PTPRG_HUMAN (757-1329): 3.11e-55: 213: 17.43
+	Hs
		121070 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		FINC_HUMAN (111-907): 2.55e-81: 297: 19.00
+	Hs
		119390 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10
+	Hs
		121108 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		PTPRG_HUMAN (757-1329): 3.11e-55: 213: 17.43
+	Hs
		572277 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		PTPRA_HUMAN (521-1304): 2.08e-110: 368: 19.78
+	Hs
		121159 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10
+	Hs
		362790 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		FINC_HUMAN (111-907): 2.55e-81: 297: 19.00
+	Hs
		362931 LEG7_HUMAN (224-354): 6.94e-39: 136: 37.04		FINC_HUMAN (111-907): 2.55e-81: 297: 19.00
+	Hs
		572281 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		PTPRG_HUMAN (757-1329): 3.11e-55: 213: 17.43
+	Hs
		572282 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		PTPRZ_HUMAN (760-1324): 8.39e-54: 209: 18.59
+	Hs
		572363 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10
+	Hs
		814954 LEG7_HUMAN (224-354): 6.94e-39: 136: 37.04		PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10
+	Hs
		572368 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		PTPRO_HUMAN (46-453): 1.96e-21: 103: 14.92