Interactor 1: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Interactor 2: KLH17 (Q6TDP4)
Kelch-like protein 17 (Actinfilin)
Gene: KLHL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 30190310
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BACK~Kelch_1, BTB~BTB, Kelch_1~Kelch_1
Common GO terms GO:0005737 - cytoplasm
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 568
Hs

1 642
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Last updated: 11Aug2025