HitPredict

Interactor 1: KLH20 (Q9Y2M5)
Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X)
Gene: KLHL20

Interactor 2: NS1BP (Q9Y6Y0)
Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3) (Kelch-like protein 39)
Gene: IVNS1ABP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.836

The method score is based on:

Property Details
Experiments 25619834, 26687681
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BACK~Kelch_1, BTB~BTB, Kelch_1~Kelch_1
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 609
Hs

1 642
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Service provided by Combinatics, Japan

Last updated: 11Aug2025