Interactor 1: KLH22 (Q53GT1)
Kelch-like protein 22
Gene: KLHL22
Interactor 2: IPP (Q9Y573)
Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27)
Gene: IPP
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BACK~BTB, BACK~Kelch_1, BTB~BTB, Kelch_1~Kelch_1 |
| Common GO terms | GO:0005737 - cytoplasm GO:0031463 - Cul3-RING ubiquitin ligase complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:1990756 - ubiquitin-like ligase-substrate adaptor activity |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
