HitPredict

Interactor 1: KLHL4 (Q9C0H6)
Kelch-like protein 4
Gene: KLHL4

Interactor 2: KLHL1 (Q9NR64)
Kelch-like protein 1
Gene: KLHL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 37495603, 30190310
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BACK~Kelch_1, BTB~BTB
Common GO terms GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 718
Hs

1 748
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Service provided by Combinatics, Japan

Last updated: 11Aug2025