HitPredict

Interactor 1: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Interactor 2: TESK2 (Q96S53)
Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2)
Gene: TESK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32707033
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~PK_Tyr_Ser-Thr
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 571
+	Hs
		468716 HS90B_HUMAN (1-504): 0: 675: 71.68		TESK2_HUMAN (1-571): 5.82e-163: 477: 100.00
+	Hs
		461843 HS90A_HUMAN (1-504): 0: 659: 62.61		TESK2_HUMAN (1-571): 5.82e-163: 477: 100.00
+	Hs
		468217 HS90B_HUMAN (1-504): 0: 675: 71.68		EPHB1_HUMAN (4-410): 2.88e-124: 390: 21.80
+	Hs
		468402 HS90B_HUMAN (1-504): 0: 675: 71.68		TESK1_HUMAN (41-558): 3.06e-126: 385: 47.62
+	Hs
		461310 HS90A_HUMAN (1-504): 0: 659: 62.61		EPHB1_HUMAN (4-410): 2.88e-124: 390: 21.80
+	Hs
		461509 HS90A_HUMAN (1-504): 0: 659: 62.61		TESK1_HUMAN (41-558): 3.06e-126: 385: 47.62
+	Hs
		468312 HS90B_HUMAN (1-504): 0: 675: 71.68		MERTK_HUMAN (61-437): 2.03e-100: 328: 25.00
+	Hs
		461412 HS90A_HUMAN (1-504): 0: 659: 62.61		MERTK_HUMAN (61-437): 2.03e-100: 328: 25.00
+	Hs
		468211 HS90B_HUMAN (1-504): 0: 675: 71.68		LIMK1_HUMAN (62-312): 5.58e-66: 228: 44.40
+	Hs
		468212 HS90B_HUMAN (1-504): 0: 675: 71.68		LIMK2_HUMAN (62-318): 8.88e-61: 214: 40.86
+	Hs
		461302 HS90A_HUMAN (1-504): 0: 659: 62.61		LIMK1_HUMAN (62-312): 5.58e-66: 228: 44.40
+	Hs
		1245570 Q6PK50_HUMAN (1-301): 1.18e-138: 405: 80.26		TESK2_HUMAN (1-571): 5.82e-163: 477: 100.00
+	Hs
		922258 H90B4_HUMAN (1-505): 0: 647: 100.00		LIMK1_HUMAN (62-312): 5.58e-66: 228: 44.40
+	Hs
		461303 HS90A_HUMAN (1-504): 0: 659: 62.61		LIMK2_HUMAN (62-318): 8.88e-61: 214: 40.86
+	Hs
		922314 H90B4_HUMAN (1-505): 0: 647: 100.00		LIMK2_HUMAN (62-318): 8.88e-61: 214: 40.86
+	Hs
		573401 ENPL_HUMAN (1-504): 0: 599: 35.70		LIMK2_HUMAN (62-318): 8.88e-61: 214: 40.86
+	At
		308476 HS905_ARATH (1-504): 0: 586: 34.48		O82754_ARATH (62-324): 1.36e-29: 125: 34.78