HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2229 Hs			1 542
+	Hs
		1206581 PRC2B_HUMAN (1-2229): 0: 638: 100.00		FBW1A_HUMAN (3-542): 2.2e-160: 471: 81.73
+	Hs
		1431720 TARA_HUMAN (34-1668): 2.8e-34: 147: 8.75		FBW1B_HUMAN (1-542): 2.27e-175: 507: 100.00
+	Hs
		875822 PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67		FBW1B_HUMAN (1-542): 2.27e-175: 507: 100.00
+	Hs
		875840 PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67		FBW1A_HUMAN (3-542): 2.2e-160: 471: 81.73
+	Mm
		965395 KMT2C_MOUSE (2-2044): 5.46e-69: 262: 9.65		WDR5_MOUSE (395-542): 1.72e-37: 142: 24.03
+	Hs
		845363 SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78		LIS1_HUMAN (155-431): 2.01e-71: 235: 22.15
+	Hs
		965097 KMT2C_HUMAN (86-2064): 1.77e-62: 240: 9.54		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Hs
		1450952 SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78		NLE1_HUMAN (348-541): 1.24e-45: 169: 24.16
+	Hs
		1403515 MINT_HUMAN (8-1813): 2.71e-32: 140: 6.95		NLE1_HUMAN (348-541): 1.24e-45: 169: 24.16
+	Hs
		1130588 NCOA6_HUMAN (3-935): 5.4e-13: 77.4: 8.33		FBXW7_HUMAN (342-536): 4.72e-52: 190: 30.00
+	Hs
		964938 EIF3A_HUMAN (962-1409): 7.88e-26: 119: 14.63		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Hs
		161502 KMT2D_HUMAN (1599-2221): 1.48e-10: 69.3: 10.43		FBXW7_HUMAN (342-536): 4.72e-52: 190: 30.00
+	Hs
		1380165 PRR36_HUMAN (1774-2218): 3.52e-09: 64.7: 10.47		FBXW7_HUMAN (342-536): 4.72e-52: 190: 30.00
+	Hs
		161486 KMT2D_HUMAN (1599-2221): 1.48e-10: 69.3: 10.43		WDR5B_HUMAN (347-541): 2.01e-49: 175: 29.41
+	Hs
		965173 CIC_HUMAN (18-1410): 3.93e-17: 90.9: 8.32		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Hs
		875607 PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Hs
		964950 NCOA6_HUMAN (3-935): 5.4e-13: 77.4: 8.33		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Hs
		161443 KMT2D_HUMAN (1599-2221): 1.48e-10: 69.3: 10.43		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Hs
		1149790 CIC_HUMAN (18-1410): 3.93e-17: 90.9: 8.32		TAF5_HUMAN (352-541): 1.47e-21: 100: 19.39