HitPredict

Interactor 1: ACK1 (Q5U2X5)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
Gene: Tnk2

Interactor 2: CDC42 (Q8CFN2)
Cell division control protein 42 homolog (EC 3.6.5.2)
Gene: CDC42

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10618719
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GTPase_binding~Ras, PK_Tyr_Ser-Thr~Ras
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0007165 - signal transduction
GO:0030425 - dendrite
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 11Aug2025