HitPredict

Interactor 1: BMR1B (O00238)
Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)
Gene: BMPR1B

Interactor 2: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10712517
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~Activin_recp, PK_Tyr_Ser-Thr~Pkinase, PK_Tyr_Ser-Thr~TGF_beta_GS, Pkinase~TGF_beta_GS
Common GO terms GO:0001649 - osteoblast differentiation
GO:0004674 - protein serine/threonine kinase activity
GO:0004675 - transmembrane receptor protein serine/threonine kinase activity
GO:0005025 - transforming growth factor beta receptor activity, type I
GO:0005524 - ATP binding
and 19 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 502
Hs

1 532
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024