HitPredict

Interactor 1: EXOC8 (Q8IYI6)
Exocyst complex component 8 (Exocyst complex 84 kDa subunit)
Gene: EXOC8

Interactor 2: EXOC2 (Q96KP1)
Exocyst complex component 2 (Exocyst complex component Sec5)
Gene: EXOC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.930

The method score is based on:

Property	Details
Experiments	28514442, 14525976, 33961781, 27173435, 24056301
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Exo84_C~Sec5
Common GO terms	GO:0000145 - exocyst GO:0000281 - mitotic cytokinesis GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006887 - exocytosis and 7 others more... GO:0006893 - Golgi to plasma membrane transport GO:0006904 - vesicle docking involved in exocytosis GO:0015031 - protein transport GO:0016020 - membrane GO:0031267 - small GTPase binding GO:0090148 - membrane fission GO:0090522 - vesicle tethering involved in exocytosis
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	725
Hs

1	924

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024