HitPredict

Interactor 1: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Interactor 2: ES8L3 (Q8TE67)
Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8-like protein 3) (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-related protein 3)
Gene: EPS8L3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	14565974
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 593
+	Hs
		1224645 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		ES8L2_HUMAN (1-589): 0: 542: 28.00
+	Hs
		996567 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		ITK_HUMAN (328-509): 2.93e-39: 154: 17.39
+	Hs
		433413 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		YES_HUMAN (351-580): 5.73e-33: 135: 12.13
+	Hs
		454841 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		FGR_HUMAN (403-580): 4.84e-28: 120: 16.40
+	Hs
		802871 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		CRKL_HUMAN (427-548): 1e-28: 118: 22.84
+	Hs
		209108 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		NCK2_HUMAN (454-564): 1.08e-23: 105: 18.12
+	Hs
		557737 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		NCK1_HUMAN (342-566): 8.48e-17: 84.3: 13.48
+	Mm
		223016 ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93		NCK2_MOUSE (342-566): 1.57e-17: 86.6: 15.88
+	Hs
		1020381 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		EPS8_HUMAN (514-592): 1.09e-14: 79.6: 32.91
+	Hs
		1224620 ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00		ES8L1_HUMAN (349-589): 3.86e-14: 77.7: 20.33
+	Mm
		995948 ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93		EPS8_MOUSE (514-592): 8.38e-14: 76.6: 32.91
+	Hs
		3146 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		A0A0S2Z4E4_HUMAN (450-592): 9.77e-34: 130: 16.97
+	Hs
		3136 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		A0A0S2Z4D7_HUMAN (450-560): 6.47e-28: 111: 18.05
+	Hs
		209180 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		NCK2_HUMAN (454-564): 1.08e-23: 105: 18.12
+	Mm
		913884 ABI2_MOUSE (1-508): 4.85e-88: 279: 61.18		EPS8_MOUSE (514-592): 8.38e-14: 76.6: 32.91
+	Hs
		557806 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		NCK1_HUMAN (342-566): 8.48e-17: 84.3: 13.48
+	Hs
		1255835 ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84		ES8L1_HUMAN (349-589): 3.86e-14: 77.7: 20.33
+	Ce
		105690 Q10929_CAEEL (3-503): 2.93e-67: 225: 28.94		G5ED33_CAEEL (529-590): 5.31e-13: 74.2: 31.75
+	Hs
		433350 SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72		YES_HUMAN (351-580): 5.73e-33: 135: 12.13
+	Hs
		203208 SYNJ1_HUMAN (38-463): 1.36e-41: 161: 11.55		NCK1_HUMAN (342-566): 8.48e-17: 84.3: 13.48