HitPredict

Interactor 1: SPT2 (Q68D10)
Protein SPT2 homolog (Protein KU002155) (SPT2 domain-containing protein 1)
Gene: SPTY2D1

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1834
+	Hs
		1314339 CBP_HUMAN (105-562): 6.02e-14: 77.9: 15.12		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		925730 SC24C_HUMAN (288-563): 5.89e-13: 74.7: 18.60		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		274190 ANR17_HUMAN (155-556): 1.81e-09: 63.6: 12.41		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		854107 SPT2_HUMAN (1-664): 1.28e-103: 332: 100.00		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Mm
		1013664 TNIK_MOUSE (72-489): 8.48e-28: 122: 15.81		ANK2_MOUSE (800-1719): 3.46e-49: 196: 12.66
+	Hs
		1461071 TNIK_HUMAN (50-490): 3.88e-32: 136: 15.23		PCLO_HUMAN (859-1831): 4.13e-14: 80.9: 9.26
+	Hs
		854358 CHD7_HUMAN (123-489): 2.9e-20: 98.7: 11.25		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		1030710 TNIK_HUMAN (50-490): 3.88e-32: 136: 15.23		ANK2_HUMAN (790-1770): 6.65e-09: 63.5: 12.86
+	Dm
		119660 M9PB30_DROME (27-554): 4.43e-09: 62.4: 10.89		M9PB30_DROME (814-1463): 1.62e-28: 128: 10.28
+	Mm
		108249 TNIK_MOUSE (72-489): 8.48e-28: 122: 15.81		G3X8Q1_MOUSE (878-1722): 2.01e-09: 65: 11.31
+	Hs
		1253860 CBP_HUMAN (105-562): 6.02e-14: 77.9: 15.12		SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50
+	Hs
		1129671 CBP_HUMAN (105-562): 6.02e-14: 77.9: 15.12		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Mm
		1455913 PCLO_MOUSE (42-576): 3.68e-11: 69: 10.05		PCLO_MOUSE (836-1825): 7.2e-16: 86.7: 10.09
+	Hs
		861238 CBP_HUMAN (105-562): 6.02e-14: 77.9: 15.12		MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90
+	Hs
		861083 SC24C_HUMAN (288-563): 5.89e-13: 74.7: 18.60		MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90
+	Hs
		161499 CBP_HUMAN (105-562): 6.02e-14: 77.9: 15.12		KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52
+	Hs
		161491 KMT2C_HUMAN (87-564): 4.25e-09: 62.4: 11.37		KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52