Protein: SPT2
Protein SPT2 homolog (Protein KU002155) (SPT2 domain-containing protein 1)

Gene: SPT2, SPTY2D1
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q68D10

Gene Ontology (top 5):
GO:0001042 - RNA polymerase I core binding
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006334 - nucleosome assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1228607

H2AW
Core histone macro-H2A.2

2

5

High-throughput

0.811

High

979819

H4
Histone H4

2

4

High-throughput

0.754

High

1228602

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

4

5

High-throughput

0.694

High

419031

H2A1B
Histone H2A type 1-B/E

1

4

High-throughput

0.691

High

1016939

H33
Histone H3.3

1

12

High-throughput

0.691

High

447106

NPM
Nucleophosmin

4

1

High-throughput

0.691

High

1228601

ZN692
Zinc finger protein 692

3

5

High-throughput

0.662

High

208282

RRP8
Ribosomal RNA-processing protein 8

3

0

High-throughput

0.634

High

841383

RBM34
RNA-binding protein 34

2

5

High-throughput

0.628

High

972450

RS14
Small ribosomal subunit protein uS11

2

4

High-throughput

0.628

High

1057773

RL18
Large ribosomal subunit protein eL18

2

1

High-throughput

0.628

High

1137065

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

2

2

High-throughput

0.628

High

998429

H31
Histone H3.1

1

12

High-throughput

0.618

High

1152328

U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

2

3

High-throughput

0.611

High

1008768

RED1
Double-stranded RNA-specific editase 1

2

5

High-throughput

0.601

High

96697

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

372280

MYC
Myc proto-oncogene protein

2

16

High-throughput

0.584

High

290597

SURF6
Surfeit locus protein 6

2

0

High-throughput

0.576

High

1199129

PKHO1
Pleckstrin homology domain-containing family O member 1

2

1

High-throughput

0.574

High

1228593

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

2

High-throughput

0.574

High

1228599

MAGBA
Melanoma-associated antigen B10

2

7

High-throughput

0.574

High

396308

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1228592

SNIP1
Smad nuclear-interacting protein 1

2

2

High-throughput

0.571

High

191673

MAGB2
Melanoma-associated antigen B2

2

7

High-throughput

0.549

High

287020

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

7

High-throughput

0.536

High

338871

CBX6
Chromobox protein homolog 6

1

4

High-throughput

0.536

High

521743

H14
Histone H1.4

1

2

High-throughput

0.536

High

686212

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.536

High

854107

KI67
Proliferation marker protein Ki-67

1

9

High-throughput

0.536

High

973210

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.536

High

975746

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.536

High

1065237

SSRP1
FACT complex subunit SSRP1

1

15

High-throughput

0.536

High

1089711

ILF3
Interleukin enhancer-binding factor 3

1

7

High-throughput

0.536

High

1099391

SRSF6
Serine/arginine-rich splicing factor 6

1

3

High-throughput

0.536

High

1130758

RRP5
Protein RRP5 homolog

1

2

High-throughput

0.536

High

1151135

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.536

High

1228600

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

1

High-throughput

0.536

High

1228604

DDX21
Nucleolar RNA helicase 2

1

6

High-throughput

0.536

High

1228609

ZBT47
Zinc finger and BTB domain-containing protein 47

1

3

High-throughput

0.536

High

1228613

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

1228619

RL36
Large ribosomal subunit protein eL36

1

2

High-throughput

0.536

High

1228620

RBM19
Probable RNA-binding protein 19

1

2

High-throughput

0.536

High

1228586

Q6FHY5
MEOX2 protein

1

20

High-throughput

0.515

High

542065

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

824192

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

855110

NOP2
28S rRNA

1

0

High-throughput

0.513

High

1228587

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.513

High

1228588

CENPU
Centromere protein U

1

0

High-throughput

0.513

High

1228594

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

428811

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.489

High

563020

MYH6
Myosin-6

1

1

High-throughput

0.489

High

657254

KALM
Anosmin-1

1

8

High-throughput

0.489

High

984437

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.489

High

1127401

FGFP1
Fibroblast growth factor-binding protein 1

1

1

High-throughput

0.489

High

1228611

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.489

High

140958

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

406275

MYCN
N-myc proto-oncogene protein

1

15

High-throughput

0.479

High

643895

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

799933

COIL
Coilin

1

1

High-throughput

0.479

High

851591

GATA4
Transcription factor GATA-4

1

10

High-throughput

0.479

High

886284

ARL4D
ADP-ribosylation factor-like protein 4D

1

7

High-throughput

0.479

High

979000

RS6
Small ribosomal subunit protein eS6

1

2

High-throughput

0.479

High

984811

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

1035697

KIF23
Kinesin-like protein KIF23

1

9

High-throughput

0.479

High

1228589

SLX4
Structure-specific endonuclease subunit SLX4

1

17

High-throughput

0.479

High

1228591

ZBT38
Zinc finger and BTB domain-containing protein 38

1

1

High-throughput

0.479

High

1228595

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1228596

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

6

High-throughput

0.479

High

1228606

NLE1
Notchless protein homolog 1

1

5

High-throughput

0.479

High

1228608

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

1228610

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1228615

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

1228616

TR150
Thyroid hormone receptor-associated protein 3

1

9

High-throughput

0.479

High

1228618

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

1228605

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

601723

HMGA1
High mobility group protein HMG-I/HMG-Y

1

2

High-throughput

0.445

High

649334

H1T
Histone H1t

1

2

High-throughput

0.445

High

765618

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.445

High

960144

RL26
Large ribosomal subunit protein uL24

1

2

High-throughput

0.445

High

967464

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.445

High

1212333

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

1228597

ZN414
Zinc finger protein 414

1

1

High-throughput

0.445

High

1228617

RBMX2
RNA-binding motif protein, X-linked 2

1

4

High-throughput

0.445

High

893930

MEOX2
Homeobox protein MOX-2

1

20

High-throughput

0.439

High

241982

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.437

High

341595

EYA4
Protein phosphatase EYA4

1

13

High-throughput

0.437

High

400989

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.437

High

821406

TCPZ
T-complex protein 1 subunit zeta

1

9

High-throughput

0.437

High

1141687

EEA1
Early endosome antigen 1

1

9

High-throughput

0.437

High

1215662

RC3H1
Roquin-1

1

2

High-throughput

0.437

High

1228612

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.437

High

1136794

MO4L2
Mortality factor 4-like protein 2

1

0

High-throughput

0.426

High

1228590

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.426

High

69951

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

1228614

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.407

High

158655

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.279

Low

348250

DCMC
Malonyl-CoA decarboxylase, mitochondrial

1

0

High-throughput

0.279

Low

615830

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.279

Low

724486

GDIA
Rab GDP dissociation inhibitor alpha

1

0

High-throughput

0.279

Low

859866

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.279

Low

960765

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.279

Low

1228598

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.279

Low

1228603

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.249

Low

652644

GNLY
Granulysin

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025