HitPredict

Interactor 1: WWC2 (Q6AWC2)
Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)
Gene: WWC2

Interactor 2: RHPN1 (Q8TCX5)
Rhophilin-1 (GTP-Rho-binding protein 1)
Gene: RHPN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1192 Hs			1 670
+	Hs
		1311634 KIBRA_HUMAN (1-1192): 0: 925: 48.79		RHPN1_HUMAN (1-670): 0: 708: 100.00
+	Hs
		1311653 KIBRA_HUMAN (1-1192): 0: 925: 48.79		LIN7C_HUMAN (452-617): 1.43e-35: 135: 21.32
+	Hs
		1311632 KIBRA_HUMAN (1-1192): 0: 925: 48.79		INADL_HUMAN (360-666): 4.37e-11: 68.4: 10.31
+	Hs
		1357014 WWOX_HUMAN (5-193): 8.82e-38: 149: 20.71		PDC6I_HUMAN (109-515): 1.4e-86: 291: 23.36
+	Hs
		1356977 ITCH_HUMAN (10-143): 1.83e-32: 138: 24.83		PDC6I_HUMAN (109-515): 1.4e-86: 291: 23.36
+	Hs
		132182 WWP2_HUMAN (3-143): 7.2e-31: 133: 23.84		PDC6I_HUMAN (109-515): 1.4e-86: 291: 23.36
+	Hs
		861700 NEDD4_HUMAN (4-295): 3.75e-18: 92.7: 14.93		PDC6I_HUMAN (109-515): 1.4e-86: 291: 23.36
+	Hs
		1356978 NED4L_HUMAN (7-163): 9.72e-18: 91.2: 14.65		PDC6I_HUMAN (109-515): 1.4e-86: 291: 23.36
+	Dm
		1486711 SUDX_DROME (3-143): 3.5e-31: 134: 23.23		Q9VUH6_DROME (109-518): 8.81e-68: 244: 22.07
+	Sc
		815499 RSP5_YEAST (30-164): 9.63e-20: 97.7: 13.42		BRO1_YEAST (109-521): 1.03e-66: 236: 19.58
+	Hs
		132330 WWP2_HUMAN (3-143): 7.2e-31: 133: 23.84		LIN7C_HUMAN (452-617): 1.43e-35: 135: 21.32
+	Mm
		1223740 MAGI3_MOUSE (6-127): 2.48e-33: 142: 33.33		DLG4_MOUSE (460-595): 1.72e-18: 91.9: 19.86
+	Hs
		1341095 WWP1_HUMAN (6-143): 3.65e-36: 150: 22.67		INADL_HUMAN (360-666): 4.37e-11: 68.4: 10.31
+	Hs
		1341088 MAGI1_HUMAN (1-97): 8.81e-33: 140: 38.53		INADL_HUMAN (360-666): 4.37e-11: 68.4: 10.31
+	Mm
		855293 SYT1_MOUSE (687-828): 5.3e-25: 111: 13.07		DLG4_MOUSE (460-595): 1.72e-18: 91.9: 19.86
+	Hs
		132175 WWP2_HUMAN (3-143): 7.2e-31: 133: 23.84		INADL_HUMAN (360-666): 4.37e-11: 68.4: 10.31
+	Hs
		1341096 SAV1_HUMAN (4-88): 4.56e-27: 116: 38.82		INADL_HUMAN (360-666): 4.37e-11: 68.4: 10.31
+	Mm
		861864 NEDD4_MOUSE (54-169): 6.58e-20: 98.1: 19.33		DLG3_MOUSE (419-592): 3.71e-16: 84.6: 16.85
+	Mm
		97734 E9PXB7_MOUSE (59-163): 3.54e-17: 89.2: 15.28		DLG3_MOUSE (419-592): 3.71e-16: 84.6: 16.85
+	Hs
		1368713 NED4L_HUMAN (7-163): 9.72e-18: 91.2: 14.65		DLG3_HUMAN (438-592): 2.62e-14: 78.5: 17.58