HitPredict

Interactor 1: LNX2 (Q8N448)
Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)
Gene: LNX2

Interactor 2: MYLIP (Q8WY64)
E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP)
Gene: MYLIP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.658

The method score is based on:

Property Details
Experiments 21516116, 29892012, 31515488
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005886 - plasma membrane
GO:0046872 - metal ion binding
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 690
Hs

1 445
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024