HitPredict

Interactor 1: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Interactor 2: RUFY1 (Q96T51)
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12)
Gene: RUFY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 161 Hs			1 708
+	Hs
		1233592 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		FYV1_HUMAN (545-708): 1.05e-38: 156: 25.56
+	Hs
		1233301 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		RUFY3_HUMAN (109-527): 1.6e-33: 136: 56.33
+	Hs
		1141690 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		EEA1_HUMAN (100-662): 7.07e-22: 103: 10.21
+	Hs
		1233451 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		FYCO1_HUMAN (152-654): 1.21e-13: 76.8: 15.58
+	Hs
		1233386 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		RUFY2_HUMAN (85-439): 1.49e-10: 66.6: 10.99
+	Hs
		1106273 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		ROCK1_HUMAN (337-638): 1.87e-10: 66.4: 13.96
+	Hs
		270820 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		ROCK2_HUMAN (348-660): 3.22e-10: 65.7: 12.81
+	Hs
		336115 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		ZFYV9_HUMAN (639-700): 4.55e-10: 65.5: 41.27
+	Hs
		1191426 LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00		GRDN_HUMAN (312-647): 7.59e-09: 61.4: 16.95