HitPredict

Interactor 1: LRFN4 (Q6PJG9)
Leucine-rich repeat and fibronectin type-III domain-containing protein 4
Gene: LRFN4

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 635 Hs			1 728
+	Hs
		1232098 VASN_HUMAN (15-516): 7.85e-62: 219: 22.78		LNX1_HUMAN (1-728): 1.34e-141: 434: 100.00
+	Hs
		1090147 LRFN4_HUMAN (17-635): 1.36e-143: 433: 100.00		PTN13_HUMAN (211-725): 8.09e-27: 119: 11.88
+	Hs
		299765 LRFN4_HUMAN (17-635): 1.36e-143: 433: 100.00		MPDZ_HUMAN (513-728): 8.19e-22: 103: 18.43
+	Hs
		1348515 LGR6_HUMAN (23-149): 4e-18: 91: 31.78		LNX1_HUMAN (1-728): 1.34e-141: 434: 100.00
+	Mm
		1223598 LRFN4_MOUSE (17-635): 1.03e-138: 420: 96.13		DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88
+	Mm
		999790 LRFN2_MOUSE (17-591): 7.41e-99: 321: 52.85		DLG3_MOUSE (146-594): 9.64e-38: 153: 17.36
+	Mm
		1281877 LRFN2_MOUSE (17-591): 7.41e-99: 321: 52.85		DLG1_MOUSE (432-728): 6.43e-36: 147: 19.60
+	Mm
		1223589 LRFN2_MOUSE (17-591): 7.41e-99: 321: 52.85		DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88
+	Hs
		1122257 VASN_HUMAN (15-516): 7.85e-62: 219: 22.78		SCRIB_HUMAN (355-725): 8.93e-41: 163: 21.25
+	Rn
		1192888 LRRC4_RAT (17-410): 1.07e-66: 232: 23.03		PARD3_RAT (204-552): 2.97e-33: 139: 18.61
+	Rn
		1192937 LRFN2_RAT (2-310): 1.47e-25: 114: 13.48		DLG3_RAT (234-594): 1.38e-37: 152: 19.95
+	Rn
		1192936 LRFN2_RAT (2-310): 1.47e-25: 114: 13.48		DLG1_RAT (438-728): 4.2e-35: 145: 19.66
+	Mm
		1180772 LRFN1_MOUSE (2-116): 8.39e-20: 96.2: 24.37		DLG1_MOUSE (432-728): 6.43e-36: 147: 19.60
+	Hs
		1122310 LRIG1_HUMAN (286-401): 1.4e-12: 73: 24.14		SCRIB_HUMAN (355-725): 8.93e-41: 163: 21.25
+	Rn
		723879 LRFN2_RAT (2-310): 1.47e-25: 114: 13.48		DLG4_RAT (581-725): 1.72e-22: 104: 22.88
+	Mm
		999793 LRC4C_MOUSE (5-82): 2.93e-09: 62.3: 19.75		DLG3_MOUSE (146-594): 9.64e-38: 153: 17.36
+	Hs
		1090196 LRFN1_HUMAN (2-116): 8.51e-20: 95.8: 24.37		PTN13_HUMAN (211-725): 8.09e-27: 119: 11.88
+	Mm
		1180771 LRFN1_MOUSE (2-116): 8.39e-20: 96.2: 24.37		DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88
+	Mm
		503541 LRC4B_MOUSE (5-82): 8.89e-11: 66.9: 20.99		DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88
+	Mm
		1223632 LRC4C_MOUSE (5-82): 2.93e-09: 62.3: 19.75		DLG4_MOUSE (581-725): 1.95e-22: 104: 22.88