HitPredict

Interactor 1: Q6PK50 (Q6PK50)
HSP90AB1 protein
Gene: HSP90AB1

Interactor 2: TRI56 (Q9BRZ2)
E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (RING finger protein 109) (Tripartite motif-containing protein 56)
Gene: TRIM56

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 755
+	Hs
		468745 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		TRI56_HUMAN (1-755): 1.88e-164: 495: 100.00
+	Hs
		461877 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		TRI56_HUMAN (1-755): 1.88e-164: 495: 100.00
+	Hs
		468774 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		TRIM2_HUMAN (1-749): 6.06e-155: 470: 18.38
+	Hs
		461905 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		TRIM2_HUMAN (1-749): 6.06e-155: 470: 18.38
+	Hs
		468318 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		TRI32_HUMAN (1-748): 1.99e-87: 290: 15.38
+	Hs
		461418 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		TRI32_HUMAN (1-748): 1.99e-87: 290: 15.38
+	Hs
		468053 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		RO52_HUMAN (17-510): 7.2e-75: 252: 13.13
+	Hs
		623394 Q6PK50_HUMAN (1-345): 9.22e-179: 501: 100.00		RO52_HUMAN (17-510): 7.2e-75: 252: 13.13
+	Hs
		461134 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		RO52_HUMAN (17-510): 7.2e-75: 252: 13.13
+	Hs
		468773 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		TRIM6_HUMAN (7-512): 2.4e-72: 245: 10.23
+	Hs
		468770 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		TRIM8_HUMAN (16-509): 3.45e-67: 233: 17.62
+	Hs
		186497 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		TRI18_HUMAN (13-399): 3.08e-62: 223: 16.43
+	Hs
		468102 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		PML_HUMAN (3-527): 5.83e-57: 211: 16.45
+	Hs
		468830 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		TRI36_HUMAN (16-351): 1.04e-53: 199: 14.81
+	Hs
		461957 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		TRI36_HUMAN (16-351): 1.04e-53: 199: 14.81
+	Hs
		461215 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		TRI23_HUMAN (19-339): 2.98e-49: 184: 20.34
+	Hs
		573523 ENPL_HUMAN (2-351): 5.57e-138: 412: 42.54		TRI68_HUMAN (8-512): 4.19e-70: 240: 11.30
+	Hs
		180687 ENPL_HUMAN (2-351): 5.57e-138: 412: 42.54		TIF1A_HUMAN (20-480): 1.57e-63: 231: 17.57
+	Hs
		573344 ENPL_HUMAN (2-351): 5.57e-138: 412: 42.54		PML_HUMAN (3-527): 5.83e-57: 211: 16.45