HitPredict

Interactor 1: EIF3F (O00303)
Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47)
Gene: EIF3F

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	16196087, 18354498
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 357 Hs			1 685
+	Hs
		475966 CSN6_HUMAN (76-357): 3.14e-101: 303: 22.73		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475500 PSMD7_HUMAN (88-356): 1.64e-95: 289: 27.27		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		176926 EIF3H_HUMAN (84-353): 3.84e-76: 240: 16.17		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		130705 PSDE_HUMAN (81-356): 5.98e-69: 220: 15.31		UBC_HUMAN (1-685): 0: 846: 100.00
+	Sc
		477476 RPN8_YEAST (90-356): 9.68e-83: 256: 26.21		UBI4P_YEAST (381-685): 5e-122: 370: 95.74
+	At
		1091969 PSD7B_ARATH (81-356): 1.01e-97: 294: 24.82		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		188941 PSD7A_ARATH (81-356): 2.56e-96: 290: 24.47		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1091853 CSN6A_ARATH (82-357): 1.37e-88: 270: 23.76		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		137953 EIF3F_ARATH (66-355): 1.47e-88: 270: 35.62		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1092172 PSDE_ARATH (82-348): 1.68e-66: 213: 15.62		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1091965 EIF3H_ARATH (82-293): 2.27e-48: 168: 15.45		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Mm
		291863 CSN6_MOUSE (76-357): 4.06e-102: 305: 22.73		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476691 PSMD7_MOUSE (88-356): 2.4e-95: 288: 27.64		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		397853 PSMD7_HUMAN (88-356): 1.64e-95: 289: 27.27		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Rn
		89029 D4AEH3_RAT (88-356): 1.3e-88: 270: 26.55		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		130837 PSDE_HUMAN (81-356): 5.98e-69: 220: 15.31		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		192886 PSDE_MOUSE (81-356): 5.98e-69: 220: 15.31		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		130693 PSDE_HUMAN (81-356): 5.98e-69: 220: 15.31		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Hs
		130704 PSDE_HUMAN (81-356): 5.98e-69: 220: 15.31		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70